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Electrophoretic Light Scattering (ELS) is a technique used to measure the electrophoretic mobility of particles in dispersion, or molecules in solution. This mobility is often converted to Zeta potential to enable comparison of materials under different experimental conditions.

The fundamental physical principle is that of electrophoresis. A dispersion is introduced into a cell containing two electrodes. An electrical field is applied to the electrodes, and particles or molecules that have a net charge, or more strictly a net zeta potential will migrate towards the oppositely charged electrode with a velocity, known as the mobility, that is related to their zeta potential.

The velocity is measured by the laser Doppler technique. There are two implementations of this. One to determine a frequency shift, which can give a full zeta potential distribution and a second known as PALS, where the phase shift is measured. PALS is a more sensitive method, but only gives an average zeta potential value.

The Zetasizer Nano uses both techniques to give the best of both worlds.

Products using Electrophoretic Light Scattering

Zetasizer range Particle and molecule size, zeta potential, molecular weight img
These systems measure:
Zeta potential, particle size & molecular weight
Particle size range:
0.3nm to 10µm
Zeta potential size range:
0.38nm to 100µm
Dispersion type:
Wet
Technology:
Dynamic light scattering, electrophoretic light scattering & static light scattering
Equipment environment:
Laboratory
See all Zetasizer products

Malvern solutions for Electrophoretic light scattering



Zeta potential - An introduction in 30 minutes Zeta potential is a physical property which is exhibited by any particle in suspension. It can be used to optimize the formulations of...
Electrophoretic Light Scattering - Overview When an electric field is applied across an electrolytic solution, charged particles suspended in the electrolyte are attracted towards the electrode...
Zeta Potential Zetasizer Nano Z/ZS/ZS90 Training Course This course focuses on Zeta Potential and measurements made using a Zetasizer Nano Z or ZS. This course begins with a general...
Measurements of protein electrophoretic mobility using the Zetasizer Nano ZSP Zetasizer Nano is the market leader in dynamic and electrophoretic light scattering technology for measurements of hydrodynamic size and electrophoretic...


 
 
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Instruments using this technology